We observe many trans-eQTLs reported in prior studies, including the monocyte-specific master regulator at the LYZ locus on chromosome 12 identified by Fairfax (rs10784774) [7], the multiple trans-effects of variation type 1 diabetes region 12q13.2 described by Fehrmann and Fairfax [5], [7], and the lupus SNP rs7917014 (tagged by rs4917014 in our data) association with CLEC4C, CLEC10A, IFIT1, and other genes highlighted by Westra [11]. Here, LYZ is linked to systemic lupus erythematosus.