Associations with the same coded allele (T) with urate levels [20], serum albumin levels [31], serum total protein levels [31], platelet counts [33], liver enzyme levels[38], cardiovascular disease risk factors [34], C-reactive protein levels [35], total cholesterol and triglyceride levels [36], chronic kidney disease [37] all had a positive direction of effect. The gene discussed is ALB; the disease is chronic kidney disease.