NCF1 and myocardial infarction: For example, the survival rate of p47phox−/− mice 4-weeks after myocardial infarction (MI) was significantly higher than that of WT mice (72% versus 48%) and the survival benefits were associated with a decline in LV dilatation and dysfunction, cardiomyocyte hypertrophy, apoptosis, and interstitial fibrosis in p47phox−/− mice [34].