Furthermore, to evaluate the influence of docetaxel on PIAS1 expression, a tissue microarray (TMA) consisting of benign and malignant prostate tissues of 14 PCa patients who received docetaxel before radical prostatectomy, as well as 14 matched treatment-naïve PCa patients [34] was immunohistochemically stained. Here, PIAS1 is linked to posterior cortical atrophy.