Hence, we could not only demonstrate that Mcl1 expression is elevated in primary and metastatic tumors which confirms previous observations by Krajewska et al. and Zhang et al. [43, 44], but were also able to demonstrate that its expression, similar to that of PIAS1, is further induced after docetaxel chemotherapy and in resistant cells. The gene discussed is PIAS1; the disease is metastatic neoplasm.