In the AdSurp-Hsp70+CIK, AdSurp-Hsp70 and AdSurp-EGFP treatment groups, the treatment efficacies for the tumor xenografts in the strongly positive Survivin subgroups were significantly better than those in the weakly positive Survivin subgroups, and the efficacy of the CIK group was not related to Survivin expression (Fig. 3B). This evidence concerns the gene BIRC5 and neoplasm.