Nuclear-YAP1 and FGF8 levels were plotted against each other, and the staining of nuclear YAP1 in high-FGF8-expressing tumors was stronger than that in low-FGF8-expressing tumors, suggesting that the expression of YAP1 is associated with FGF8 level in colorectal cancer (Figure 6E-F). This evidence concerns the gene YAP1 and colorectal cancer.