They have been reported to function during early mammary placode formation in the developing embryo (that is, Msx2, Tbx3, Wnt3a, and Fgfr1) or they are involved in breast cancer cell migration, invasion, and proliferation (that is, Barx2, Pdgfrb, Bmp6, and Jak3) [27]-[36]. This evidence concerns the gene MSX2 and breast carcinoma.