Interestingly, maternal uniparental disomy of chromosome 16 usually associated with mosaic trisomy 16, and thus resulting in even higher dosage of FOXF1 is associated with pulmonary hypoplasia, congenital heart defects, tracheosophageal fistula, gut malrotation, and renal agenesis in addition to intrauterine growth restriction [37], suggesting FOXF1 expression higher than that in constitutional duplications may influence development of organs typically affected in patients with ACDMPV. The gene discussed is FOXF1; the disease is Pulmonary hypoplasia.