IRS1 and metabolic syndrome: Total IRS‐1 content of muscle was not different in the metabolic syndrome subjects as displayed in Fig. 1B. Phosphorylation of tyrosine at position 896 (Tyr896) was not different and the ratio of phosphorylation at Tyr896 to total IRS‐1 averaged 17% less in the metabolic syndrome, but this decrease in the ratio was not statistically significant.