Furthermore, three microRNAs, miR-27a, miR-96, and miR-182, have all been found to directly target FOXO1 and regulate endogenous FOXO1 protein expression in breast cancer cells, while suppression of these microRNAs resulted in an increase in FOXO1 protein and a decrease in cell growth [22]. The gene discussed is FOXO1; the disease is breast carcinoma.