INS and metabolic syndrome: Activation of AMPK is also participating in the hypolipidemic effects of curcumin, which has been involved in the stimulation of fatty acid oxidation (increasing the expression of carnitine palmitoyl transferase-1) and inhibition of lipogenesis (decreasing the expression of glycerol-3-phosphate acyltransferase-1) in adipose tissue of obese mice treated with curcumin [44]; these data are in agreement with our findings about the reduction in the dyslipidemia of diabetic rats treated with curcumin-enriched yoghurt, which did not differ from those observed with the insulin treatment (Table 2).