CXCL8 and autoimmune polyendocrinopathy: Notably, the absolute levels of IL-6 (both mRNA and protein) in cells exposed to APS-IgG in our experiment were similar to those described by Mulla et al.12,13 The difference in our experiment was the inclusion of cells exposed to HC-IgG and as these cells also secreted IL-8 or IL-6 at similar levels we were unable to confirm a specific effect of the APS-IgG samples on these outcomes.