CDO1 and cancer: For example, we have identified N-methyl-D-aspartate receptor type 2A (NMDAR2A) [6], deafness, autosomal dominant 5 (DFNA5) [7], Oncostatin M receptor-β (OSMR) [8], and cysteine dioxygenase 1 (CDO1) [9] as cancer-prone frequently methylated genes in colorectal cancer (CRC) by using pharmacological unmasking microarrays [1], [2].