Furthermore, ST6GAL1 promoter hypermethylation of six CpG sites (located from -98 bp to +584 bp with respect to the TSS, i.e. covering the MSP analyzed region) was confirmed in bladder cancer samples underscoring a homogenous methylation pattern within the ST6GAL1 promoter locus (Figure 5B) compared to normal solid tissues. This evidence concerns the gene ST6GAL1 and urinary bladder cancer.