Assessment of correlations employing Kendall tau b revealed a significant positive correlation between epidermal thickness and NGF+ NF (tau 0.600, p = 0.045) and a significant positive correlation between SCORAD and NF-mast cell contacts in lesional skin (tau 0.894, p = 0.008) as well as between itch and NGF+ NF in non-lesional (tau 0.466, p = 0.028) and itch and NF-mast cell contacts (tau 0.745, p = 0.022) in lesional AD skin. Here, NGF is linked to Alzheimer disease.