We evaluated the E-cadherin, Vimentin expression in response to SB431542 treatment, E-cadherin and vimentin protein levels were significant differences in the SB431542 treated ESCC cells as compared with controls, (Fig.2D, H, L, p<0.05, Y axis: optical densities of test bands versus β-actin bands). Here, CDH1 is linked to esophageal squamous cell carcinoma.