TNF and coinfection: Indeed, our baseline analysis confirmed the strong association of sCD14 with age [35], the link of HCV co-infection with three soluble markers (IP-10, sICAM-1 and sVCAM-1) [36], and identified a striking association of several cytokines, TRAIL and TNF-α among other, with the cART regimen (PI- or NNRTI-based).