Serum levels of IL-17, IL-6, and IL-1β were also significantly higher in SLE patients with anti-B19-NS1 IgG (514.19±135.34 pg/ml, 439.58±140.85 pg/ml, and 46.44±21.51 pg/ml, respectively) than in those without anti-B19-NS1 IgG (63.17±6.66 pg/ml, p<0.005; 85.34±28.22 pg/ml, p<0.05; and 10.69±4.65 pg/ml, p<0.01, respectively). Here, IL1B is linked to systemic lupus erythematosus.