Figure 7 shows the survival Kaplan Meier curves of the three treatment groups. Survival time was considered as the number of days that elapsed from tumor induction (day 0) to the day that tumor mass reached a volume of 850 mm3. We selected the latter as the end event because animals had to be sacrificed shortly after according to the regulation of the animal's ethic committee. A significant difference (p<0.01) in tumor volume was observed between the group treated with MGMT-kB1 LODN and both control groups. Here, MGMT is linked to neoplasm.