Mice treated with 665 μCi 177Lu-DOTA-30F11 developed fatal anemia and thrombocytopenia as these mice died by week 2 after RIT injections [mean hemoglobin (Hb) 2.6±1.3 g/dL (16.3% of untreated controls), mean platelet count 7.3±1.8 K/μL (0.7% of untreated controls), compared to mean Hb 16.0±1.5 g/dL [difference of 13.4 g/dL ([11.3-15.6], p<0.0001)] and mean platelets 1061.2±191 K/μL in untreated control mice [difference of 1054.0 K/μL ([824.5–1283.4], p<0.0001)]; Fig. 5B and C]. This evidence concerns the gene GSTM1 and Thrombocytopenia.