For this analysis an additional group of patients who had undergone a clinical follow-up was studied to determine whether MEOX2 and TWIST1 overexpression in the tumoral tissue was associated with the levels of H3K27me3 vs. H3K27Ac and H3K4me3 and might determine the prognosis and/or responsiveness to oncologic treatment in NSCLC patients. The gene discussed is MEOX2; the disease is non-small cell lung carcinoma.