FCGR3B and vasculitis: In the investigation of the association between FCGR3B CNV and AAV, it is noteworthy that the approach they used for statistical analysis; in a previous paper, an association with AAV and low FCGR3B CNV by Quantitative Polymerase Chain Reaction was utilized (70), but analyzing a UK Caucasian vasculitis cohort with a triple paralog ratio test the association was not confirmed, suggesting that the initial finding may have been a false-positive resulting deriving from the lack of robustness in the qPCR assay (71).