MT-ND2 and amyotrophic lateral sclerosis: In accordance with our findings, ND2 genomic DNA levels in human postmortem spinal cord motor neurons of ALS patients were also not altered compared to controls, whereas mitochondrial genomic DNA-levels for mitochondrially coded cytochrome oxidase and ND4 were significantly lower in ALS (Keeney and Bennett, 2010)—probably due to mitochondrial DNA deletions that occur preferentially in the ND4 gene (He et al., 2002).