Findings consistent with an important role for CaBP4 in the regulation of phototransduction have come from the study of a CaBP4 mouse knock-out and also the presence of mutations in human CaBP4 [164], [165] and in CaV1.4 [166], which cause retinal disorders including congenital night blindness. The gene discussed is CABP4; the disease is congenital stationary night blindness.