CD44 and neoplasm: Among the perioperative variables recorded for univariate analysis were: presence of CD44, CD54, and vimentin, loss of E-cadherin and β-catenin expression, with a tumor size of 5 cm or more, more advanced T-stage, and a more advanced TNM stage with early recurrence to late recurrence Multivariate analysis was employed to identify the independent risk factors for overall recurrence.