Although not analyzing early events following infection, one study using NOD/scid mice with human fetal thymus xenograft focused on innate immune responses to EBV and demonstrated a role of EBV-induced CD8+ NKT cells in the suppression of tumorigenesis by EBV-associated Hodgkin lymphoma and nasopharyngeal carcinoma cells [114]. Here, CD8A is linked to Hodgkins lymphoma.