Univariate analysis identified the following significant prognostic factors for poor OS: DM, serum AFP level ≥400 ng/ml, serum albumin level <35 g/L, serum GGT level ≥50 U/L, ascites, incomplete tumor capsule, macrovascular invasion, tumor size ≥10 cm, tumor number ≥3, poor degree of tumor cell differentiation, and operation time >180 min (Table S2). This evidence concerns the gene ALB and neoplasm.