As shown in Table 1 and Fig.2F, in consistent with abnormal expression of Aurora-A, PAK7 overexpression was also detected in esophageal cancers, and more importantly, PAK7 expression was significantly positively correlated with Aurora-A level, underscoring the physiological relevance of the relationship between Aurora-A and PAK7 in ESCC. Here, PAK5 is linked to esophageal squamous cell carcinoma.