To our best knowledge, no previous studies have investigated the combined influence of CAT C262T, GPX1 Pro198Leu, MnSOD Ala16Val, GSTT1, GSTM1, and GSTP1 Ile105Val variants on CML nor the influence of these genetic polymorphisms on clinical phases of the disease and prognostic factors. This evidence concerns the gene GSTP1 and chronic myelogenous leukemia, BCR-ABL1 positive.