The CAT C262T, GPX1 Pro198Leu, MnSOD Ala16Val, GSTM1, GSTT1, and GSTP1 polymorphisms investigated had no impact on the risk of CML with respect to gender (P value = 0.22, P value = 0.31, P value = 0.68, P value = 0.23, P value = 0.64, and P value = 0.68, resp). This evidence concerns the gene SOD2 and chronic myelogenous leukemia, BCR-ABL1 positive.