No significant correlation was observed between the positive expression rates of FHIT (46 and 73%) and BRCA2 (33 and 63%), between the positive expression rates of FHIT (46 and 73%) and MLH1 (27 and 61%), and between the positive expression rates of FHIT (46 and 73%) and p53 (52 and 46%) in the oesophageal cancer tissues of all patients. This evidence concerns the gene MLH1 and carcinoma of esophagus.