The decreased expression level of PDCD5 has been observed in various human tumors, and is correlated with high-grade astrocytic gliomas (9), a higher Gleason grade in prostate cancer (6) and an advanced International Federation of Gynecologists and Obstetricians stage and poorer survival in epithelial ovarian carcinomas (8). This evidence concerns the gene PDCD5 and Familial prostate cancer.