A previous study determined that 50% of CML patients exhibited DAPK1 methylation, and this was not correlated with age, hematological parameters, chromosomal abnormalities or the type and quantity of the BCR/ABL transcripts, however, it was correlated with gender and CML phase (26). This evidence concerns the gene ABL1 and chronic myelogenous leukemia, BCR-ABL1 positive.