CpG methylation in the DAPK1 promoter region has been detected in a range of solid cancers, such as non-small cell lung cancer (34), leiomyosarcoma (35), nasopharyngeal carcinoma (36), and hematological malignancies, such as follicular lymphoma (37) and CML (24,25,38). The gene discussed is DAPK1; the disease is hematologic disorder.