NPPB and familial dilated cardiomyopathy: This study showed that through the inhibition of the p38 MAPK signaling pathway activity, BPS reduced the expression of inflammatory factors such as TNF-α, HIF-1α, and MMP-9; inhibited myocardial cell apoptosis; and decreased the expression of BNP and ANP, thus delaying the progression of DCM and protecting cardiac function.