IL-1, IL-2, TNF-α, IFN-γ, TGF-β and IL-6 protein levels were significantly decreased in the ACE2-uMSC group compared with those of the BLM group (P<0.05); whereas, IL-10 was significantly increased (P<0.05) (Fig. 4B). The gene discussed is IL6; the disease is Bloom syndrome.