Candidiasis was the only significant predictor of immune suppression measured as CD4 < 350 cells/mm3, (OR = 2.56, 1.52-4.30, p < 0.001), (Table 4) The PPV of OHL, kaposi sarcoma, melanotic hyperpigmentation and candidiasis were 47.4%, 41.9%, 32.2% and 48.2% respectively. This evidence concerns the gene CD4 and sarcoma.