We further conducted immunohistochemical assay to detect KIF18A protein in 32 cases of HCC tissues, and found that 21 of 32 (65.6%) cancer tissues had KIF18A positive staining while only 8 of 32 (25.0%) ANLT and none of 8 normal liver tissues from hepatic hemangioma had KIF18A positive staining (Fig. 2). This evidence concerns the gene KIF18A and cancer.