The results showed that size of tumor >5 cm (HR, 3.119; 95% CI, 1.795-5.421; P <0.001), III-IV of TNM stage (HR, 1.650; 95% CI, 1.076-2.529; P=0.022) and high KIF18A expression (HR, 1.602; 95% CI, 1.029-2.579; P =0.031) were independent predictors for DFS (Table 3). The gene discussed is KIF18A; the disease is neoplasm.