In a study of subjects with acute asthma, stable asthma, and healthy controls, induced sputum gene expression for TLR3, IP-10/CXCL10, and IL-10 was increased in viral, compared with nonviral, acute asthma, and levels of IP-10/CXCL10 and IL-10 mRNA expression were correlated with the mRNA expression of TLR3 in viral acute asthma [150]. The gene discussed is CXCL10; the disease is asthma.