Following up a number of SNPs within the HLA region identified by three previous NPC GWAS, Tang and colleagues compared allele frequencies between 1400 EBV IgA-VCA-positive NPC cases, 1300 EBV-positive controls and 1300 EBV-negative controls (defined by the presence of anti-VCA-IgA in blood). This evidence concerns the gene CD79A and nasopharyngeal carcinoma.