CD4 and infection: In aggregate, the HIV RNA+/Ab- envelope viruses had significantly lower replication AUC compared to the chronic (log AUC difference −1.3, 95% CI −2.6 – 0.002, p =0.03) but non-significant differences compared to the early (log AUC difference −0.7, 95% CI −2.1 – 0.6, p =0.3) infection envelopes in mature MDDC – CD4+ T cell co-cultures.