As the important role of miR-126 we found on VEGF-A in gastric cancer, we further validated the in vitro data by using a xenograft mouse model, showing that tumor growth as well as VEGF-A and MVD was significantly suppressed in Lenti-miR-126 stablely transfected SGC-7901 xenografts as compared with control group. This evidence concerns the gene VEGFA and neoplasm.