PIK3CA and head and neck squamous cell carcinoma: Their sequencing findings were in agreement with preliminary data from The Cancer Genome Atlas (TCGA) HNSCC study, where a multitude of potentially druggable targets including amplifications (e.g. FGFR1, CCND1, MYC, EGFR), deletions (e.g. PTEN), activating mutations (e.g. PIK3CA) and fusions (e.g. FGFR3/TACC3) were observed.