We later examined the expression pattern of 4 genes, FZD4, FZD5, Wnt5a and RHOU, in the noncanonical Wnt/Ca2+ signaling pathway in primary AML cells from newly diagnosed AML patients (AML-ND), AML patients in complete remission (AML-CR) and normal controls (CON). This evidence concerns the gene FZD4 and acute myeloid leukemia.