In Japanese, fasting levels of total and intact GLP-1 were lower in patients with T2DM than the control group (15.5 ± 1.7 vs. 15.7 ± 1.0; and 0.2 ± 0.1 vs. 0.7 ± 0.2 pM, respectively) [9]. The gene discussed is GCG; the disease is type 2 diabetes mellitus.