In the multivariate analysis, anemia was independently associated with HTPR (odds ratio [OR] = 2.16, 95% confidence interval [CI] = 1.38–3.37; p = 0.001; Table 3) as assessed by the VerifyNow P2Y12 assay (PRU ≥252.5). The gene discussed is P2RY12; the disease is anemia (phenotype).