In brief, patients with high GS had higher percentage of smoking, hypertension, dyslipidemia and DM, higher level of TC, LDL-C, Lp(a), apoB, fasting blood glucose, hemoglobin A1C (HbA1C), and lower levels of HDL-C, apoA1 and LVEF. The gene discussed is APOA1; the disease is diabetes mellitus.