Our results, such as a higher basal ECS volume both in situ and in vivo, smaller cell swelling during exposure to more severe stimuli as well as a faster/higher [K+]o increase in GFAP/EGFP/α-Syn−/− mice after cardiac arrest, indicate that the tissue and diffusion properties of GFAP/EGFP and GFAP/EGFP/α-Syn−/− mice are indistinguishable from those observed in α-Syn+/+ and α-Syn−/− mice, respectively [12]. This evidence concerns the gene GFAP and cardiac arrest.