PIK3CA mutation was more prevalent in patients with KRAS mutation than in patients with wild-type KRAS [31], whereas in this report, a low frequency of KRAS mutation was found in metastatic or recurrent cervical carcinomas, and in squamous cell carcinomas specifically, no KRAS mutation was identified in any of the 26 tested patients (Table 1). This evidence concerns the gene PIK3CA and cervical carcinoma.