All myxofibrosarcoma cell lines were incubated with indicated doses of L-alanosine for 72 h; this attenuated the cell viability in only the MTAP-deficient parent NMFH-2 and OH931 cells yielding IC50 values of approximately 1 μM and 5 μM, respectively, but not in the MTAP-expressing NMFH-1 cells (Figure 5B). Here, MTAP is linked to myxofibrosarcoma.