MAPT and amyloidosis: Although the present study was small, it adds to the body of evidence (Oikawa et al., 2010; Heuer et al., 2012) that support the neuropathology of the aged cynomolgus monkey as a potential model for studies of spontaneous disease of Alzheimer-type, especially the amyloid-related brain pathology and also suggests the potential for further study of p-tau mediated pathology in the species (Walker, 1997; Levine and Walker, 2006; Oikawa et al., 2010; Heuer et al., 2012).