Zhang et al. (2008) performed a proteomics-discovered multianalyte profile (MAP) in CSF on 95 control subjects, 48 patients with probable AD, and 40 patients with probable PD, and concluded that the optimal MAP leading to the correct diagnosis was composed of the following proteins in order of contribution: tau, BDNF, IL-8, Aβ42, β2-microglobulin, vitamin D binding protein, apoA2, and apoE. The gene discussed is APOE; the disease is Alzheimer disease.